Redox-Neutral α-Sulfenylation of Secondary Amines: Ring-Fused N,S-Acetals
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چکیده
منابع مشابه
Redox-Neutral α-Sulfenylation of Secondary Amines: Ring-Fused N,S-Acetals
Secondary amines react with thiosalicylaldehydes in the presence of catalytic amounts of acetic acid to generate ring-fused N,S-acetals in redox-neutral fashion. A broad range of amines undergo α-sulfenylation, including challenging substrates such morpholine, thiomorpholine, and piperazines. Computational studies employing density functional theory indicate that acetic acid reduces the energy ...
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ژورنال
عنوان ژورنال: Organic Letters
سال: 2014
ISSN: 1523-7060,1523-7052
DOI: 10.1021/ol501509b